Dr Nick Sculthorpe

Senior Lecturer in Exercise Physiology

Hamilton Campus
Tel 01698 283100


I completed my first degree and Liverpool John Moores University and progressed to an MSc at Manchester Metropolitan University. Following graduation from Manchester I won a funded PhD at the University of Glamorgan. This scholarship was related to using Echocardiography to examine the effects of different kinds of exercise training on markers of cardiac structure and function compared to patients with different kinds of heart disease. Subsequent to my PhD, my interest in the use of Ultrasound in Sport and Exercise Science has widened to include studies encompassing vascular and musculoskeletal health. In addition to this I have a significant interest in the use of performance enhancing drugs, and specifically the abuse and consequent side effects of Androgenic Anabolic Steroids.

I am a research active academic and have been returned in all of the Research Assessment Exercise for which I have been eligible. (see below for list of publications). I remain a a full time research active academic and along side my research I have written and validated courses at all levels including the first degree in the country to include externally recognized exercise professional awards from basic instruction through to G.P. referral. In addition I have written and validated Foundation, undergraduate and Masters level programmes.

  • Qualifications

    1st degree(s):
    BSc Sport and Exercise Science, Liverpool John Moores University, 1997

    Higher degree(s):
    PhD Exercise Physiology, University of Glamorgan 2002

    Other (professional or PGCert etc.):
    MSc Exericse Physiology, Manchester Metropolitan University, 1998

  • Teaching Interests
    Cardiovascular Physiology
    Exercise and Health Screening
    Drugs in Sport
    Nutrition and Sports Performance
  • Research Interests
    Cardiovascular Physiology
    Exercise and Models of Successful Ageing
    Athletic Heart and Cardiac Mechanics
    Nutritional Ergogenic Aids
  • Research activity output chapters
    FM Grace N Sculthorpe and J Baker (2012)The effects of the non-therapeutic anabolic androgenic steroids use on cardiac structure and function. In F. a. Grace (Ed.), In Perspectives on Anabolic Steroids and Doping in Sport and Health. London: Nova Science .

    DS Hughes, N Sculthorpe, M Lewis (2012). Testosterone and the molecular regulation of skeletal muscle. In F. a. Grace (Ed.), Perspectives on Anabolic Steroids and Doping in Sport and Health. Nova Science.
  • Research activity output journals
    Buchan, D., Boddy, L., Despres, J., Grace, F., Sculthorpe, N., & C Mahoney. (2015). Utility of the hypertriglyceridemic waist phenotype in the cardiometabolic risk assessment of youth stratified by body mass index . Pediatric Obesity.

    Davies, P., Grace, F., Lewis, M., & Sculthorpe, N. (2015). Observation of Age-Related Decline in the Performance of the Transverse Abdominis Muscle. Physical Medicine and Rehabilitation .

    Grace, F., Herbert, P., Ratcliffe, J., New, K., Baker, J., & Sculthorpe, N. (2015). Age related vascular endothelial function following lifelong sedentariness: positive impact of cardiovascular conditioning without further improvement following low frequency high intensity interval training. Physiological Reports .

    Hayes, L., Grace, F., Baker, J., & Sculthorpe, N. (2015). Exercise-induced responses in salivary testosterone, cortisol, and their ratios in men: a meta-analysis. Sports Medicine .
    Hayes, L., Sculthorpe, N., Herbert, P., Baker, J., Hullin, D., & Grace, F. (2014). Salivary testosterone measurement does not identify biochemical hypogonadism in aging men: a ROC analysis. Journal of Physiology and Biochemistry.

    Hayes, L., Sculthorpe, N., Herbert, P., Baker, J., Spagna, R., & Grace, F. (2015). Six weeks of conditioning exercise increases total, but not free testosterone in lifelong sedentary aging men.

    Sculthorpe, N., Taylor, L., & Grace, F. (2015). Prolonged androgenic anabolic steroid (AAS) induced QT interval shortening: a suitable screening tool? Drug testing and Analysis .

    Angell, P., Chester, N., Sculthorpe, N., Whyte, G., George, K., & Somauroo, J. (2012). Performance enhancing drug abuse and cardiovascular risk in athletes: implications for the clinician. British Journal of Sports Medicine .
  • Research activity output conference presentations
    • Hughes, D.C., Sculthorpe, N., Sharples, A.P. & Lewis, M.P. (2012). The effects of Testosterone on molecular markers of hypertrophy in C2C12 skeletal muscle cells. Biomedical Basis of Elite Performance. London, UK.
    • Richards, J., Kerr, C., Oxborough, D., George, K. and Sculthorpe, N. (2012) Left Ventricular Determinants of VO2max in a Heterogenesis Group of Healthy Males. The Biomedical Basis of Elite Performance 2012.
    • Sculthorpe N., Solomon AM, Sinanan ACM, Boloux PGM, Grace F, Lewis MP. (2011) Androgens affect myogenesis in vitro and increase local IGF-I expression.  Med Sci Sports and Exerc.
    • Richards, J., Kerr, C., Biswell, K., Oxborough, D., George, K. and Sculthorpe, N. (2011) The Effect of Six Weeks Resistance Training on Left Ventricular Tissue Velocity. BASES Annual Conference 2011.


  • Research activity output source of funding
    2012 Volac Ltd. Whey protein supplementation and muscle health. (Awarded - £17,000 May 2012)

    2011 Actiflow™ Lower limb activation in long haul flights to reduce the risk of deep vein thrombosis (Award £20,000 (Co-Investigator))

    2011 UEFA Research in Football - Effects of environmental conditions on match official performance. (€10,000 (Co-Applicant))

    2010 Maximuscle Ltd - Impact of sports nutrition supplementation on metabolic rate and hunger. (Award £5,000 – Co-Applicant)

    2009 Research Informed Teaching Round 4 (RiTs): Ultrasound upgrade (Award £19,050)

    2007 The Higher Education Academy, Leisure Sport and Tourism Network (LTSN) Embedding research based teaching in the first year of a sport science course. How does it affect students engagement, their confidence as a learner and understanding of the research process. (Award £2500)

    2006 Research Informed Teaching Round 2 (RiTs): Validation of diagnostic criteria for the differentiation of pathological and physiological left ventricular hypertrophy (Awarded £3,500)

    2005 Royal Society Partnership grant (with Delapre PS). (2005). Scientific Partnership in Schools (Award £1,000).
  • Consultancy Interests
    Health Screening
    Digital Health Development
    Performance Testing
    Nutritional Supplementation
  • Useful information





    • Group Head – Applied Sport and Exercise Science Research Group 2010-2012.  Outputs -13 papers £37,000 grant income approved, £20,000 pending descisions.
    •  Group Head – Molecular and Cellular Research Group 2011-2012. Outputs – 7 Papers, £30,000 grant income approved, £250,000 pending.
    • Director of Studies Dr J Richards (PhD; Awarded May 2012) Cardiac effects of different training modalities in sedentary males.
    • Director of Studies Mr P Davies (PhD; post upgrade) In vivo and in vitro models of ageing in postural muscles.
    • Director of Studies Miss R Lancaster (PhD; post upgrade) Acute effects of high intensity exercise on cardiac function, strain and strain rate. 
    • 2nd Supervisor Mr D Hughes (PhD; upgrade August 2012) Molecular effects of testosterone on administration on myocyte proliferation and differentiation.
    • Director of Studies Mrs C Barford (PhD; 2012 start)  Effectiveness of community delivered training programmes on indicies of core strength and co-ordination.